• Babita Ghai, Sameer Sethi, Deepika Bansal, and Jagat Ram.
• Anesthesia Department, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
• J Clin Anesth. 2015 Dec 1; 27 (8): 627-31.

Study ObjectiveEnd-tidal concentration of sevoflurane for I-gel insertion in children has not been studied. This study was designed to determine the sevoflurane EC50 and EC95 for I-gel placement in children as compared with classic laryngeal mask airway (CLMA) placement.DesignThe design was a prospective, randomized controlled study.SettingsThe setting was single tertiary care center.PatientsPediatric subjects of either sex aged 1.5-8 years, weighing 10-20 kg having American Society of Anesthesiologists physical status I/II of undergoing elective cataract surgery were included in the study.InterventionInduction and maintenance of anesthesia were achieved with sevoflurane and oxygen with preservation of spontaneous breathing. Children were randomly subjected to either I-gel size 2 (group I) or CLMA size 2 (group II) insertion. The target end-tidal sevoflurane concentration (ET SEVO) was maintained for 8-10 minutes before supraglottic airway device was inserted in both the groups. In the first child, the ET SEVO was kept at 2% and was increased or decreased by 0.2% in the next child depending on the previous child's response according to Dixon method. After each supraglottic airway device insertion, child was observed for 1 minute for any "movement" or "no movement."MeasurementsThe measurements were EC50 and EC95 for I-gel and CLMA placement in children.Main ResultsEC50 and EC95 for group I were 0.94% (0.83%-1.06%) and 1.26% (1.12%-1.66%) and for group II were 1.9% (1.70%-2.1%) and 2.54% (2.24%-3.41%), respectively.ConclusionI-gel insertion in children can be accomplished at nearly half ET SEVO (0.94%) of that required for CLMA insertion (1.9%).Copyright © 2015 Elsevier Inc. All rights reserved.

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