• Clin Neurol Neurosurg · Dec 2001

    Case Reports

    Episodic cervical dystonia associated with gastro-oesophageal reflux. A case of adult-onset Sandifer syndrome.

    • M Shahnawaz, L R van der Westhuizen, and R F Gledhill.
    • Department of Neurology, Medunsa Ga-Rankuwa, PO Box 108, 0204, Medunsa, South Africa.
    • Clin Neurol Neurosurg. 2001 Dec 1; 103 (4): 212-5.

    AbstractSandifer syndrome is a dystonic movement disorder described in children with severe gastro-oesophageal reflux. We now report a patient who had the features of Sandifer syndrome first developing in adult life. Onset of dystonic episodes followed closely the occurrence of a Bell's palsy, while symptoms of peptic oesophagitis had been present for several months beforehand. Successful symptomatic treatment of gastro-oesophageal reflux was accompanied by cessation of the dystonic episodes. Possible pathophysiological mechanisms of the abnormal movements in Sandifer syndrome are discussed.

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