• Andrea Saporito, Luciano Anselmi, Alain Borgeat, and José A Aguirre.
• Anesthesiology Service, Bellinzona Regional Hospital, Switzerland. Electronic address: andrea.saporito@eoc.ch.
• J Clin Anesth. 2016 Aug 1; 32: 119-26.

Study ObjectiveShort-acting regional anesthetics have already been successfully used for peripheral nerve blocks in an ambulatory surgery setting. However, the impact on direct and indirect perioperative costs comparing 2 different short-acting local anesthetics has not been performed yet.DesignObservational, prospective, case-control, cost-minimization study.SettingOperating room, regional hospitalPatientsOne hundred adult American Society of Anesthesiologists status I-III patients scheduled for popliteal block after minor ambulatory foot surgery.InterventionsApplication of 30 mL chloroprocaine 3% or of 30 mL mepivacaine 1.5% for anesthesia.MeasurementsCost-minimization evaluation. Direct and indirect perioperative costs were calculated. Block success, onset time and block duration, patient satisfaction, and unplanned outpatient visits or readmissions after discharge were also assessed.Main ResultsOnset time (sensory: 4.3 ± 2.4 vs 11.5 ± 3.2 minutes; motor: 7.1 ± 3.7 vs 18.4 ± 4.5 minutes) and block duration (sensory: 105 ± 26 vs 317 ± 46 minutes; motor: 91 ± 25 vs 216 ± 31 minutes) were significantly shorter (P < .001) when chloroprocaine 3% was used. This translated to P < .001, basically due to a faster discharge home 55 ± 1 vs 175 ± 2 minutes; P < .001) in favor of chloroprocaine 3%, without negatively affecting either block efficacy or patients satisfaction. There were no unplanned outpatient visits or readmissions and no complications in the follow-up at 6 weeks.ConclusionsWe conclude that the more expensive chloroprocaine 3% for ambulatory foot surgery can reduce total perioperative costs and reduce length of stay in outpatient patients. Moreover, the saved time and personal resources could be used for additional cases, further increasing the revenues of an ambulatory surgical center.Copyright © 2016 Elsevier Inc. All rights reserved.

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