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Hematol. Oncol. Clin. North Am. · Oct 2014
ReviewFrontline Therapy for Patients with Multiple Myeloma not Eligible for Stem Cell Transplantation.
- Philippe Moreau, Cyrille Hulin, and Thierry Facon.
- Hematology Department, UMR892, University Hospital, Place Ricordeau, Nantes 44093, France. Electronic address: philippe.moreau@chu-nantes.fr.
- Hematol. Oncol. Clin. North Am. 2014 Oct 1; 28 (5): 829-38.
AbstractConsiderable progress has been recently made in the treatment of elderly patients with multiple myeloma (MM). In Europe the combination of thalidomide with melphalan and prednisone and of bortezomib with melphalan and prednisone are 2 standards of care for frontline therapy for elderly patients. In United States the combination of lenalidomide and dexamethasone is the preferred option in this setting. This article focuses on more recent therapeutic approaches in older MM patients, not eligible for high-dose therapy and autologous stem cell transplantation.Copyright © 2014 Elsevier Inc. All rights reserved.
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