• Childs Nerv Syst · Apr 2010

    Review

    The physiology behind direct brain oxygen monitors and practical aspects of their use.

    • Eileen Maloney-Wilensky and Peter Le Roux.
    • Clinical Research Division, Department of Neurosurgery, University of Pennsylvania, 330 S. 9th Street, Philadelphia, PA 19107, USA.
    • Childs Nerv Syst. 2010 Apr 1; 26 (4): 419-30.

    IntroductionSecondary neuronal injury is implicated in poor outcome after acute neurological insults. Outcome can be improved with protocol-driven therapy. These therapies have largely been based on monitoring and control of intracranial pressure and the maintenance of an adequate cerebral perfusion pressure.DiscussionIn recent years, brain tissue oxygen partial pressure (PbtO2) monitoring has emerged as a clinically useful modality and a complement to intracranial pressure monitors. This review examines the physiology of PbtO2 monitors and practical aspects of their use.

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