-
Review Comparative Study
Helicobacter pylori: why it still matters in 2005.
- M Brian Fennerty.
- Division of Gastroenterology, Oregon Health & Science University, Portland, OR, USA.
- Cleve Clin J Med. 2005 May 1; 72 Suppl 2: S1-7; discussion S14-21.
AbstractDespite falling prevalence rates in the developed world, H pylori is still present in the United States and is particularly prevalent among racial minorities and recent immigrants. H pylori infection is clearly associated with an increased risk of peptic ulcer disease, gastric cancer, and MALT lymphoma, and it is associated with some cases of uninvestigated dyspepsia. Identification and eradication of H pylori improves outcomes in patients with peptic ulcer disease and causes tumor regression in patients with MALT lymphoma. It is uncertain whether H pylori eradication will improve outcomes in patients with gastric cancer. Decision analytic models suggest that a test-and-treat strategy for H pylori is rational and cost-effective for patients with uninvestigated dyspepsia.
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