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Historical Article
A brief history of blood filtration: clot screens, microaggregate removal, and leukocyte reduction.
- Samuel T Wortham, Girolamo A Ortolano, and Barry Wenz.
- Pall Medical, Pall Corporation, East Hills, NY 11548, USA. Sam_Wortham@pall.com
- Transfus Med Rev. 2003 Jul 1; 17 (3): 216-22.
AbstractA historical perspective of the evolution of blood filtration is presented. Topics addressed include recognition of aggregates in blood as mediators of morbidity, targeted for removal with gross clot screens, and evolution through the implementation of universal leukocyte reduction. Future directions for the development of blood filters are also described.
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