• J Emerg Med · Jan 1985

    Clinical Trial Controlled Clinical Trial

    Lidocaine reduces intravenous diazepam pain.

    • R D Herr, L Ampel, and R Natonson.
    • J Emerg Med. 1985 Jan 1; 3 (5): 341-4.

    AbstractWe studied 41 consecutive patients receiving intravenous (IV) diazepam in the preoperative holding area to evaluate whether low-dose IV lidocaine could ameliorate pain of the diazepam injection. In a double-blind trial we found 1 cc of 1% lidocaine effective versus placebo at lowering the incidence of pain from 80% to 5% (P less than .001) and recommend its routine use as an antecedent to IV diazepam.

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