• Zhonghua yi xue za zhi · Jun 2010

    [Significances of NT-proBNP and hs-CRP in heart failure].

    • Li Wang, Shan-You Hu, Xiao Wu, and Xue-Feng Jü.
    • Department of Emergency Medicine, Jiading Branch of Renji Hospital, Shanghai Jiaotong University Medical College, Shanghai 201800, China. wangli@189.cn
    • Zhonghua Yi Xue Za Zhi. 2010 Jun 15; 90 (23): 1635-6.

    ObjectiveTo detect the level changes of plasma N-terminal B-type natriuretic peptide (NT-proBNP) and high-sensitivity C-reactive protein (hs-CRP) in patients with heart failure (HF) and explore their clinical correlations and prognostic significances.MethodsA total of 100 cases of HF patients were selected along with 20 age and gender-matched controls. The levels of NT-proBNP and hs-CRP were tested.ResultsThe levels of NT-proBNP were significantly higher in HF patients than the controls. And the difference was statistically significant (P < 0.01). In congestive HF patients, the elevating magnitude of plasma NT-proBNP level showed a significantly positive correlation with that of hs-CRP during the same period.Conclusion(1) The level of NT-proBNP is significantly higher in HF patients. And it can be used as one of auxiliary diagnostic indicators. (2) The level of NT-proBNP in conjunction with hs-CRP can predict the prognosis of HF patients.

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