• Y Nakata, T Goto, Y Ishiguro, K Terui, Y Niimi, and S Morita.
• Department of Anesthesia, Teikyo University School of Medicine, Ichihara Hospital, Chiba, Japan. ynakata@med.teikyo-u.ac.jp
• J Clin Anesth. 1999 Jun 1; 11 (4): 285-9.

Study ObjectiveTo determine whether pulse wave velocity (PWV), which is a useful indicator of cardiovascular disease, can predict the hemodynamic responses to anesthesia and surgical stimulation in surgical patients.DesignProspective, randomized study.SettingOperating rooms at a university hospital.Patients30 ASA physical status I and II female patients presenting for elective gynecologic surgery.InterventionPatients who received one of the following anesthesia techniques were studied; isoflurane, sevoflurane and sevoflurane with nitrous oxide (N2O).Measurements And Main ResultsPatients underwent preoperative PWV measurements using an automatic PWV measurement device. Systolic blood pressure and heart rate levels were recorded at baseline, during anesthesia, and at skin incision. PWV had no significant correlation with percent changes of systolic blood pressure or heart rate, even after controlling the choice of anesthetic drugs.ConclusionsPreoperative PWV fails to predict hemodynamic responses to anesthesia and to surgical stimulation.

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