• Paolo Viganò, Stefano Carlo Maria Picozzi, Alfio Giuberti, Marilena Casu, Vittorio Manganini, Luciano Mazza, and Guido Raffaele Strada.
• Urology Department, San Gerardo Hospital, Monza, Italy.
• Arch Ital Urol Androl. 2007 Dec 1; 79 (4): 155-7.

AbstractNumb chin syndrome is a sensory neuropathy characterized by numbness involving the distribution of the mental nerve that could be an uncommon manifestation of metastatic malignancy. Bony metastases are common in patients with advanced prostate carcinoma and involving preferentially vertebrae, sternum, pelvic bones, ribs and femurs. We report a case in an 82-year-old man presenting a history of mental neuropathy as the isolated presenting symptom of a widespread metastatic prostate cancer Numb chin syndrome was describe in some reviews as a late component of a previously diagnosed disease but this report underline the importance of this neuropathy as the isolated presenting symptom of a widespread metastatic prostate cancer. This event is very rare and enumerates four cases in the world literature.

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