• Spinal cord · Oct 2003

    Case Reports

    Treatment of spasticity in a spinal cord-injured patient with intrathecal morphine due to intrathecal baclofen tolerance--a case report and review of literature.

    • B M Soni, R M Mani, T Oo, and S Vaidyanathan.
    • Regional Spinal Injuries Centre, Southport and Ormskirk NHS Trust, Southport, UK.
    • Spinal Cord. 2003 Oct 1; 41 (10): 586-9.

    Study DesignCase report.ObjectiveTo report treatment of spasticity in a spinal cord-injured person with intrathecal morphine after the person developed tolerance to intrathecal baclofen.MethodSpasticity in a 36-year-old man with T6 complete paraplegia was treated with increasing doses of intrathecal baclofen. When he developed tolerance to intrathecal baclofen, he was given continuous infusion of morphine intrathecally.SettingRegional Spinal Injuries Centre, UK.ResultsSpasticity was adequately controlled by intrathecal morphine.ConclusionIn spinal cord-injured patients with severe spasticity, who become tolerant to intrathecal baclofen, treatment with intrathecal morphine may be useful.

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