• Ocul. Immunol. Inflamm. · Apr 2011

    Case Reports

    Topical podophyllum-induced toxic anterior uveitis.

    • Kavitha Avadhani, Padmamalini Mahendradas, Rohit Shetty, and Bhujang K Shetty.
    • Uveitis and Ocular Immunology Services, Narayana Nethralaya, Bangalore, India. kavithaviswa@gmail.com
    • Ocul. Immunol. Inflamm. 2011 Apr 1; 19 (2): 118-20.

    ObjectiveTo report a case of toxic anterior uveitis probably secondary to the use of topical podophyllum.DesignCase report, interventional.MethodsThe authors present a 78-year-old male with acute anterior uveitis that developed within a couple of hours of application of topical podophyllum. In vivo confocal microscopy showed unique findings that disappeared following treatment with topical steroids alone. The patient reapplied podophyllum 2 months later and a recurrence of uveitis was noted.ResultsA score of 7 was obtained using the adverse drug reaction probability scale, suggesting that the anterior uveitis is a probable adverse reaction to topical podophyllum.ConclusionsAnterior uveitis may occur after topical application of podophyllum.

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