• J Clin Anesth · Sep 2016

    Case Reports

    Bivalirudin anticoagulation for minimal invasive transapical transcatheter aortic valve replacement in a patient with antiphospholipid antibodies.

    • Andreas Koster, Stephan Ensminger, Marios Vlachojannis, and Ingvild Birschmann.
    • Institute of Anesthesiology, Heart and Diabetes Center NRW, Bad Oeynhausen, Ruhr-University Bochum, Germany. Electronic address: akoster@hdz-nrw.de.
    • J Clin Anesth. 2016 Sep 1; 33: 373-5.

    AbstractThe occurrence of lupus anticoagulant is associated with the hazard of developing an antiphospholipid syndrome, a severe prothrombotic condition which may particularly occur after major surgical trauma. This disease requires certain considerations regarding surgical strategy and anticoagulation management. We describe the perioperative management of a patient scheduled for elective aortic valve replacement and diagnosed for having antiphospholipid antibodies. The procedure was successfully performed using a minimally invasive approach via transapical aortic valve replacement and anticoagulation with the nonreversible short-acting direct thrombin Inhibitor bivalirudin.Copyright © 2016 Elsevier Inc. All rights reserved.

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