• Koji Ishii, Tetsuji Makita, Hikoma Yamashita, Shoji Matsunaga, Daiji Akiyama, Kouko Toba, Katsumi Hara, Koji Sumikawa, and Tetsuya Hara.
• Department of Anesthesia, Sasebo City General Hospital, Sasebo, Japan; Department of Anesthesiology, Nagasaki University School of Medicine, Nagasaki, Japan. Electronic address: soukenbicha141kouji@yahoo.co.jp.
• J Clin Anesth. 2016 Sep 1; 33: 428-31.

Study ObjectivePostoperative delirium (POD) is a common complication of anesthesia. The incidence of POD in elderly patients ranges from 37% to 53%, and POD increases the morbidity and mortality of elderly patients. However, the effects of anesthetics on POD are not well known. The present study aimed to compare the incidence of POD resulting from propofol and sevoflurane anesthesia.DesignDouble-blind prospective study.SettingOperating room and postoperative recovery area.PatientsThirty patients in the sevoflurane anesthesia group and 29 in the propofol anesthesia group.MeasurementsStatistical analyses were performed using Microsoft Excel 2010 for Windows 7 (Microsoft Corporation, Redmond, Wash). Statistical analysis was performed using Fisher exact test and Student t test.Main ResultsThe incidence of POD in the propofol anesthesia (6.9%) was significantly less than that observed in the sevoflurane anesthesia (26.7%; 038).ConclusionIn comparison with sevoflurane anesthesia, propofol anesthesia is associated with a lower incidence of POD in elderly patients.Copyright © 2016 Elsevier Inc. All rights reserved.

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