• Neurol. Sci. · May 2007

    Headache and spontaneous low cerebrospinal fluid pressure syndrome.

    • E Mea, M Savoiardo, L Chiapparini, G Casucci, V Bonavita, G Bussone, and M Leone.
    • Istituto Neurologico Carlo Besta, Via Celoria 11, I-20133, Milan, Italy.
    • Neurol. Sci. 2007 May 1; 28 Suppl 2: S232-4.

    AbstractWe examined 59 consecutive patients presenting between 1993 and 2006 at our centre diagnosed with headache associated with spontaneous intracranial hypotension syndrome (SIH). Thirty-six (61%) patients were women; the mean age was 47 years (range 20-68). Cerebral MRI with contrast confirmed SIH in all patients. Headache characteristics were obtained by direct semistructured interview; in a minority of cases information was completed retrospectively through a phone call. All SIH patients suffered from headache. Early recognition of SIH may avoid dangerous worsening due to delayed diagnosis. Orthostatic headache, the main symptom, suggests the diagnosis.

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