• Samantha R Warnakulasuriya, Simon J Davies, R Jonathan T Wilson, and David R A Yates.
• York Teaching Hospital NHS Foundation Trust, Wigginton Road, York, North Yorkshire, United Kingdom, YO31 8HE.
• J Clin Anesth. 2016 Nov 1; 34: 600-8.

Study ObjectiveThis study aims to investigate if there is equivalence in volumes of fluid administered when intravenous fluid therapy is guided by Pleth Variability Index (PVI) compared to the established technology of esophageal Doppler in low-risk patients undergoing major colorectal surgery.DesignRandomized controlled trial.SettingOperating room.PatientsForty low-risk patients undergoing elective colorectal surgery.InterventionPatients were monitored by esophageal Doppler and PVI probes and were randomized to have fluid therapy directed by using one of these technologies, with 250 mL boluses of colloid to maintain a maximal stroke volume, or a PVI of less than 14%.MeasurementsAbsolute volumes of fluid volumes given intraoperatively were measured as were 24 hours fluid volumes. Perioperative measurements of lactate and base excess were recorded as were postoperative complications.Main ResultThere was no significant difference between PVI and esophageal Doppler groups in mean total fluid administered (1286 vs 1520 mL, P=.300) or mean intraoperative fluid balance (+839 v+1145 mL, P=.150).ConclusionsPVI offers an entirely non-invasive alternative for goal-directed fluid therapy in this group of patients.Copyright © 2016 Elsevier Inc. All rights reserved.

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