• Acta Neurol. Scand. · Mar 2000

    Case Reports

    Giant negative T waves in Guillain-Barré syndrome.

    • F Yoshii, R Kozuma, M Haida, Y Shinohara, M Yoshitake, S Abe, and S Handa.
    • Department of Neurology, Tokai University School of Medicine, Kanagawa, Japan.
    • Acta Neurol. Scand. 2000 Mar 1; 101 (3): 212-5.

    AbstractA Guillain-Barré syndrome patient showed giant negative T waves on electrocardiography at the height of the disease, with large left ventricular hypokinesis on echocardiography and extensive defects on 123I-meta-iodobenzylguanidine myocardial scintigraphy. Gamma-globulin improved the neurological symptoms, and the above abnormalities resolved. We speculate that cardiac sympathetic nerve endings were transiently damaged, with consequent myocardial injury, due to norepinephrine toxicity.

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