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- J P van den Berg, H E M Vereecke, J H Proost, D J Eleveld, J K G Wietasch, A R Absalom, and M M R F Struys.
- Department of Anesthesiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands j.p.van.den.berg@umcg.nl.
- Br J Anaesth. 2017 Jan 1; 118 (1): 44-57.
AbstractThis review describes the basics of pharmacokinetic and pharmacodynamic drug interactions and methodological points of particular interest when designing drug interaction studies. It also provides an overview of the available literature concerning interactions, with emphasis on graphic representation of interactions using isoboles and response surface models. It gives examples on how to transform this knowledge into clinically and educationally applicable (bedside) tools.© The Author 2016. Published by Oxford University Press on behalf of the British Journal of Anaesthesia. All rights reserved. For Permissions, please email: journals.permissions@oup.com.
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