• Jorrit Slaman, Annet Dallmeijer, Henk Stam, Heleen Russchen, Marij Roebroeck, Rita van den Berg-Emons, and Learn2Move Research Group.
• Department of Rehabilitation Medicine and Physical Therapy, Research Lines MoveFit & Transition Into Adulthood, Erasmus MC, University Medical Center, Rotterdam, The Netherlands. Electronic address: j.slaman@erasmusmc.nl.
• Arch Phys Med Rehabil. 2013 Nov 1; 94 (11): 2227-33.

ObjectivesTo determine whether the 6-minute walk test (6MWT) is predictive of peak oxygen consumption (Vo(2)peak) and whether the 6MWT is a clinically applicable alternative to cardiopulmonary exercise testing (CPET) in ambulatory adolescents and young adults with cerebral palsy (CP).DesignCross-sectional.SettingUniversity hospital and rehabilitation centers.ParticipantsAdolescents and young adults with CP (N=41) classified in Gross Motor Function Classification System (GMFCS) level I or II.InterventionsNot applicable.Main Outcome MeasuresThe covered distance during 6 minutes was measured with a 6MWT. The Vo(2)peak was obtained with CPET on a cycle ergometer.ResultsUnivariate linear regression analysis was used to study the relationship between the outcomes of both tests. A multiple linear regression analysis was performed to determine whether Vo(2)peak could be predicted by the 6MWT, sex, body mass, and GMFCS level. A significant relationship (P<.01) was found between the outcomes of the 6MWT and CPET, with an explained variance of 21%. The multiple linear regression analysis showed an explained variance of 58% and a standard error of estimate (SEE) corresponding to 18% of the mean Vo(2)peak.ConclusionsThe 6MWT is poorly related to Vo(2)peak in ambulatory adolescents and young adults with CP. Because of a high SEE, the multiple regression model did not allow for prediction of Vo(2)peak from the 6MWT in ambulatory adolescents and young adults with CP.Copyright © 2013 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

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