• Ala A Alhowary, Khaled El-Radaideh, Anas Al-Rusan, Diab Bani Hani, Wail Khraise, Ahmad Al Omari, and Firas Alzoubi.
• Department of Anesthesiology, Faculty of Medicine, Jordan University of Science and Technology, PO Box 953, Irbid 21110, Jordan. Electronic address: aaalhowary@just.edu.jo.
• J Clin Anesth. 2017 Feb 1; 36: 80-83.

ObjectiveThe purpose of the present study was to compare the effects of inhalational anesthesia to those of total intravenous anesthesia on intraoperative electrically evoked compound action potential (e-ECAP) thresholds in children undergoing cochlear implantation.Study DesignRandomized prospective study.SettingTertiary referral teaching hospital.PatientsForty children aged 6 months to 17years with bilateral severe-to-profound sensorineural hearing loss and undergoing cochlear implantation were enrolled in the study.InterventionPatients were randomly assigned (1:1 ratio) into 2 groups to receive inhalational or total intravenous anesthesia.MeasurementsThe e-ECAP measurements were obtained with neural response telemetry software.Main ResultsAll electrodes showed lower e-ECAP thresholds under propofol, and results were statistically significant for the apical electrodes (P<.05). There was no statistical difference in the impedances between the 2 groups. Propofol minimally affected the e-ECAP. In contrast, the impedance was not affected by anesthesia.ConclusionVolatile anesthetics result in higher e-ECAP thresholds in children, suggesting that e-ECAP thresholds acquired during inhalational anesthesia overestimate auditory nerve stimulation levels, which may cause discomfort postoperatively and adversely affect the child's adaptation to the implant. We recommend the use of total intravenous anesthesia for the measurement of the e-ECAP thresholds during cochlear implant surgery.Copyright © 2016 Elsevier Inc. All rights reserved.

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