• M Ferreruela, J M Raurich, J A Llompart-Pou, A Colomar, and I Ayestarán.
• Servei de Medicina Intensiva, Hospital Universitari Son Espases, Palma de Mallorca, España.
• Med Intensiva. 2017 Nov 1; 41 (8): 461-467.

ObjectiveWe evaluated the effect of changes in FiO2 on the bias and accuracy of the determination of oxygen consumption (V˙O2) and carbon dioxide production (V˙CO2) using the E-COVX monitor in patients with mechanical ventilation.DesignDescriptive of concordance.SettingIntensive Care Unit.Patients Or ParticipantsPatients with mechanical ventilation.InterventionsWe measured V˙O2 and V˙CO2 using the E-COVX monitor. Values recorded were the average in 5min. Two groups of 30 patients. We analyzed: 1) the reproducibility in the measurement of V˙O2 and V˙CO2 at FiO2 0.4, and 2) the effect of the changes in FiO2 on the measurement of V˙O2 and V˙CO2. Statistical analysis was performed using Bland and Altman test.Variables Of Main InterestBias and accuracy.Results1) FiO2 0.4 reproducibility: The bias in the measurement of V˙O2 and V˙CO2 was 1.6 and 2.1mL/min, respectively, and accuracy was 9.7 to -8.3% and 7.2 to -5.2%, respectively, and 2) effect of FiO2 on V˙O2: The bias of V˙O2 measured at FiO2 0.4 and 0.6 was -4.0mL/min and FiO2 0.4 and 0.8 was 5.2mL/min. Accuracy between FiO2 0.4 and 0.6 was 11.9 to -14.1%, and between FiO2 0.4 and 0.8 was 43.9 to -39.7%.ConclusionsThe E-COVX monitor evaluates V˙O2 and V˙CO2 in critical patients with mechanical ventilation with a clinically acceptable accuracy until FiO2 0.6.Copyright © 2017 Elsevier España, S.L.U. y SEMICYUC. All rights reserved.

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