• Journal of critical care · Oct 2017

    Multicenter Study

    Hopelessness: Independent associations with health-related quality of life and short-term mortality after critical illness: A prospective, multicentre trial.

    • Lotti Orwelius, Margareta Kristenson, Mats Fredrikson, Sten Walther, and Folke Sjöberg.
    • Departments of Intensive Care, Linköping University, County Council of Östergötland, Sweden; Clinical and Experimental Medicine, Linköping University, County Council of Östergötland, Sweden. Electronic address: lotti.orvelius@regionostergotland.se.
    • J Crit Care. 2017 Oct 1; 41: 58-63.

    PurposeTo assess the independent associations between ability to cope and hopelessness with measures of health-related quality of life (HRQoL) and their effects on mortality up to 3 years after discharge in patients who have been treated in an intensive care unit (ICU).MethodsA prospective, cross-sectional multicenter study of 980 patients. Ability to cope, hopelessness, and HRQoL were evaluated using validated scales. Questionnaires were sent to patients 6, 12, 24, and 36 months after discharge from ICU.ResultsAfter adjustment, low scores for ability to cope and high scores for hopelessness were both related to poorer HRQoL for all subscales (except for coping with bodily pain). Effects were in the same range as coexisting disease for physical subscales, and stronger for social and mental subscales. High scores for hopelessness also predicted mortality up to 3 years after discharge from ICU (p<0.001).ConclusionsThe psychological factors ability to cope and hopelessness both strongly affected HRQoL after ICU care, and this effect was stronger than the effects of coexisting disease. Hopelessness also predicted mortality after critical illness. Awareness of the psychological state of patients after a stay in ICU is important to identify which of them are at risk.Copyright © 2017 Elsevier Inc. All rights reserved.

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