• Chun Fai Chiang, HasanM ShahnazMSDepartment of Anaesthesiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. Electronic address: shahnaz@ummc.edu.my., Sin Wan Tham, Sebastian Sundaraj, Ahmad Faris, and Nagappan Ganason.
• Department of Anaesthesiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.
• J Clin Anesth. 2017 Jun 1; 39: 828682-86.

Study ObjectiveThe purpose of this investigation was to determine if a slower speed of spinal anaesthesia injection would reduce the incidence of hypotension.Study DesignRandomised controlled trial.SettingTertiary level hospital in Malaysia.Patients77 patients undergoing elective Caesarean delivery.InterventionDiffering speeds of spinal injection.MeasurementsSystolic blood pressure was assessed every minute for the first 10min and incidence of hypotension (reduction in blood pressure of >30% of baseline) was recorded. The use of vasopressor and occurrence of nausea/vomiting were also recorded.Main Results36 patients in SLOW group and 41 patients in FAST group were recruited into the study. There was no significant difference in blood pressure drop of >30% (p=0.497) between the two groups. There was no difference in the amount of vasopressor used and incidence of nausea/vomiting in both groups.ConclusionIn our study population, there was no difference in incidence of hypotension and nausea/vomiting when spinal injection time is prolonged beyond 15s to 60s.Trial RegistrationClinicalTrials.govNCT02275897. Registered on 15 October 2014.Copyright © 2017 Elsevier Inc. All rights reserved.

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