• Zheng Ye, Jascha Rüsseler, Ivonne Gerth, and Thomas F Münte.
• CAS Key Laboratory of Mental Health, Institute of Psychology, Beijing, China; CAS Center for Excellence in Brain Science and Intelligence Technology, Shanghai, China.
• Neuroscience. 2017 Jul 25; 356: 1-10.

AbstractDyslexia is an impairment of reading and spelling that affects both children and adults even after many years of schooling. Dyslexic readers have deficits in the integration of auditory and visual inputs but the neural mechanisms of the deficits are still unclear. This fMRI study examined the neural processing of auditorily presented German numbers 0-9 and videos of lip movements of a German native speaker voicing numbers 0-9 in unimodal (auditory or visual) and bimodal (always congruent) conditions in dyslexic readers and their matched fluent readers. We confirmed results of previous studies that the superior temporal gyrus/sulcus plays a critical role in audiovisual speech integration: fluent readers showed greater superior temporal activations for combined audiovisual stimuli than auditory-/visual-only stimuli. Importantly, such an enhancement effect was absent in dyslexic readers. Moreover, the auditory network (bilateral superior temporal regions plus medial PFC) was dynamically modulated during audiovisual integration in fluent, but not in dyslexic readers. These results suggest that superior temporal dysfunction may underly poor audiovisual speech integration in readers with dyslexia.Copyright © 2017 IBRO. Published by Elsevier Ltd. All rights reserved.

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