• Am J Drug Alcohol Abuse · May 2003

    Case Reports

    Two cases of severe gamma-hydroxybutyrate withdrawal delirium on a psychiatric unit: recommendations for management.

    • Mark H Rosenberg, Laurie J Deerfield, and Edward M Baruch.
    • Department of Psychiatry, School of Osteopathic Medicine, University of Medicine and Dentistry of New Jersey, Cherry Hill, New Jersey 08002-2000, USA. markrosenberg@bigfoot.com
    • Am J Drug Alcohol Abuse. 2003 May 1; 29 (2): 487-96.

    AbstractMany psychiatric professionals are unfamiliar with gamma-hydroxybutyrate (GHB), an increasingly popular drug of abuse. GHB withdrawal can lead to psychosis and agitation, and patients may present to psychiatric facilities for treatment. Withdrawal may progress to delirium, with the potential for severe or even fatal medical complications. Therefore, it is imperative for psychiatric professionals to understand how to treat these patients. In this article, we describe two cases of severe GHB withdrawal syndrome that were treated in our inpatient psychiatric unit. These are among the most severe cases reported. Pertinent literature is reviewed and suggestions for treatment are discussed.

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