• Journal of anesthesia · Dec 2017

    Case Reports

    Epidural patch with autologous platelet rich plasma: a novel approach.

    • Berrin Gunaydin, Muberra Acar, Gokcen Emmez, Didem Akcali, and Nil Tokgoz.
    • Department of Anesthesiology, Gazi University School of Medicine, 06500, Besevler-Ankara, Turkey. gunaydin@gazi.edu.tr.
    • J Anesth. 2017 Dec 1; 31 (6): 907-910.

    AbstractWe aimed to perform an epidural patch using platelet rich plasma (PRP), which has the potential to regenerate and heal tissues via degranulation of platelets, in a 34-year-old parturient suffering from persistent post-dural puncture headache (PDPH) after failed epidural blood patch (EBP). After her admission to our unit, we reconfirmed the clinical and radiologic diagnosis of PDPH. Cranial MRI with contrast showed diffuse pachymeningeal thickening and contrast enhancement with enlarged pituitary consistent with intracranial hypotension. Clinical and radiological improvements were observed 1 week after the epidural patch using autologous PRP. Therefore, we recommend using autologous PRP for epidural patching in patients with incomplete recovery after standard EBP as a novel successful approach.

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