• Tomasz Czarnik, Aneta Czarnik, Ryszard Gawda, Maciej Gawor, Maciej Piwoda, Maciej Marszalski, Magdalena Maj, Olimpia Chrzan, Rahim Said, Maja Rusek-Skora, Marta Ornat, Kamil Filipiak, Jakub Stachowicz, Robert Kaplon, and Miroslaw Czuczwar.
• Department of Anesthesiology and Critical Care, PS ZOZ Wojewodzkie Centrum Medyczne w Opolu, Aleja Witosa 26, 45-418 Opole, Poland. Electronic address: tczarnik@mac.com.
• J Crit Care. 2018 Feb 1; 43: 294-299.

PurposeThe objective of this study was to assess the vitamin D kinetics in critically ill patients by performing periodic serum vitamin D measurements in short time intervals in the initial phase of a critical illness.Materials And MethodsWe performed vitamin D serum measurements: at admission and then in 12-hour time intervals. The minimum number of vitamin D measurements was 4, and the maximum was 8 per patient.ResultsA total of 363 patients were evaluated for participation, and 20 met the inclusion criteria. All patients had an initial serum vitamin D level between 10.6 and 39ng/mL. Nineteen patients had vitamin D levels between 10 and 30ng/mL, which means that they had vitamin D insufficiency or deficiency, and only one patient had a normal vitamin D serum plasma level. We observed that the median of the vitamin D level decreases until the fourth measurement then stabilizes around the 4th and 5th measurement and then appears to increase unevenly. The highest drop is at the very beginning.ConclusionsThe vitamin D serum level is changeable in the initial phase of a critical illness. We hypothesize that the serum vitamin D concentration can mirror the severity of illness.Copyright © 2017 Elsevier Inc. All rights reserved.

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