• Asian Cardiovasc Thorac Ann · Aug 2010

    Clinical outcomes of medical treatment of acute type A intramural hematoma.

    • Sadanari Sawaki, Yuichi Hirate, Shinichi Ashida, Akira Takanohashi, Kei Yagami, and Masato Usui.
    • Department of Cardiovascular Surgery, Nagoya Ekisaikai Hospital, Aichi, Japan. sa_sawaki@ybb.ne.jp
    • Asian Cardiovasc Thorac Ann. 2010 Aug 1; 18 (4): 354-9.

    AbstractA retrospective study was performed in 30 patients who were treated for type A intramural hematoma from 1999 to 2008, of whom 24 were initially treated without surgical intervention. These 24 patients were followed up for 3.3 +/- 3.5 years (range, 0 days to 10.0 years). Four hospital deaths occurred (hospital mortality, 16.7%), there were 2 late deaths, and 2 other patients needed an operation during the follow-up period. The event-free survival rate (freedom from death or surgery) at 5 years was significantly lower in patients with maximal aortic diameter > or =48 mm than in those with diameters <48 mm (28.6% +/- 17.1% vs. 88.2% +/- 7.8%). Maximal aortic diameter > or =48 mm and computed tomography findings of a small intimal defect were significant predictors of rupture or progression of ascending aortic dissection. The outcome of medical treatment for type A intramural hematoma was acceptable during both the early and late periods, but patients with a relatively large aortic diameter or an intimal defect in the ascending aorta have a high probability of adverse outcome, and must be considered for surgery.

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