• Spine · Aug 2018

    The Efficacy of Brace Treatment for Thoracolumbar Kyphosis in Patients with Achondroplasia.

    • Leilei Xu, Yetian Li, Fei Sheng, Chao Xia, Yong Qiu, and Zezhang Zhu.
    • Department of Spine Surgery, the Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.
    • Spine. 2018 Aug 1; 43 (16): 1133-1138.

    Study DesignA retrospective study.ObjectivesThe aim of this study was to evaluate the outcome of brace treatment in the correction of thoracolumbar kyphosis (TLK) for patients with achondroplasia and to determine the factors associated with bracing efficacy.Summary Of Background DataBrace treatment has been used to correct TLK in patients with achondroplasia. However, there was a paucity of knowledge concerning its effectiveness.MethodsA total of 33 achondroplasic patients treated by bracing were included in this study. Radiographic parameters including TLK, lumbar lordosis, curve magnitude, apical vertebral translation (AVT), percentage of apical vertebral wedging, pelvic tilt (PT), and pelvic incidence were recorded for each patient at the visit. Comparison of these parameters between the initial visit and the final visit was performed using the Student t test. Factors associated with the correction of TLK were evaluated using the logistic regression analysis.ResultsThe mean age at presentation was 27.5 ± 13.4 months. The mean period of treatment was 32.2 ± 15.7 months, and the mean period of follow-up was 25.7 ± 11.3 months. At the initial visit, the mean value of TLK and the percentage of apical vertebral wedging were 41.7 ± 15.4° and 61.4% ± 16.2%, respectively. At the final visit, the TLK and apical vertebral wedging were remarkably reduced to 29.5 ± 20.8° and 52.1% ± 18.7%, respectively. The logistic regression analysis showed that initial TLK, AVT, percentage of apical vertebral wedging, and PT were independent factors associated with the correction of TLK.ConclusionBrace treatment can effectively correct TLK and restore the morphology of apical vertebral body for patients with achondroplasia. Large TLK, severe apical vertebral wedging, presence of AVT, and low PT may be indicative of an unfavorable outcome, which should be taken into account at the initiation of bracing.Level Of Evidence4.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…