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Gynecol. Endocrinol. · Nov 2014
Case ReportsGonadotroph adenoma causing ovarian hyperstimulation syndrome in a premenopausal woman.
- Jowita Halupczok, Bożena Bidzińska-Speichert, Agnieszka Lenarcik-Kabza, Grzegorz Zieliński, Alicja Filus, and Maria Maksymowicz.
- Department of Endocrinology, Diabetology and Isotope Therapy, Wroclaw Medical University , Wroclaw , Poland .
- Gynecol. Endocrinol. 2014 Nov 1; 30 (11): 774-7.
IntroductionGonadotroph adenomas occur commonly in middle-aged adults without any specific endocrinological symptoms. To date, only 30 cases of gonadotropinoma causing ovarian hyperstimulation syndrome in pre-menopausal women have been reported.Case ReportA 37-year old woman with pituitary macroadenoma and hyperprolactinaemia was admitted to the Department of Endocrinology, Diabetology and Isotope Therapy. She presented with recurrent ovarian cysts, menstrual disturbances, headaches, visual impairment and galactorrhea. Her endocrine profile showed normal values of FSH, elevated concentrations of estradiol and suppressed LH levels. Transsphenoidal resection of the tumor tissue resulted in normalization of the hormone values and improvement in the clinical picture.ConclusionsGonadotroph adenomas should be considered in the differential diagnosis in premenopausal women with OHSS.
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