• Læknablađiđ · Jun 2010

    Review Case Reports

    [Acute abdominal pain caused by acute intermittent porphyria - case report and review of the literature].

    • Brynhildur Tinna Birgisdottir, Hilmar Asgeirsson, Steinunn Arnardottir, Jon Johannes Jonsson, and Brynjar Vidarsson.
    • Lyflaekningasvioi Landspitala, Reykjavik.
    • Laeknabladid. 2010 Jun 1; 96 (6): 413-18.

    AbstractWe describe a case of acute intermittent porphyria in a woman who presented repeatedly with abdominal pain. Porphyrias are caused by decreased enzyme activity in the heme biosynthetic pathway leading to overproduction of heme precursors if demand increases. This can cause symptoms such as abdominal pain, nausea and vomiting, constipation, tachycardia and hypertension. Treatment includes removal of causative factors, administration of carbohydrates or hemin to reduce the production of heme precursors as well as symptomatic treatment.

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