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Hematol. Oncol. Clin. North Am. · Aug 2011
ReviewThe role of surgery in advanced renal cell carcinoma: cytoreductive nephrectomy and metastasectomy.
- Jose A Karam and Christopher G Wood.
- Department of Urology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.
- Hematol. Oncol. Clin. North Am. 2011 Aug 1; 25 (4): 753-64.
AbstractRenal cell carcinoma (RCC) is considered a relatively rare malignancy worldwide. Around a third of patients with RCC present with metastatic disease, and among those patients treated with nephrectomy with curative intent, more than one-third develop metastases during postoperative follow-up. Due to the absence of curative medical treatments for metastatic RCC, surgery remains the mainstay of therapy. Surgery plays a key role in two aspects: cytoreductive nephrectomy to remove the primary renal tumor in the presence of known metastatic disease, and metastasectomy to remove distant metastatic foci in patients with metastatic RCC.Copyright © 2011 Elsevier Inc. All rights reserved.
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