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- L Pironi, C Zolezzi, E Ruggeri, F Paganelli, A Pizzoferrato, and M Miglioli.
- First Internal Medicine Unit, Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy. pironi@med.unibo.it
- Nutrition. 2000 Apr 1; 16 (4): 272-7.
Abstract6 mo afterward. Long-HPN was assessed only at baseline. In short-HPN, there was a hyperkinetic turnover at baseline. At follow-up, OC was similar to baseline, whereas cross-links, urinary calcium and magnesium decreased (P < 0.03), and parathyroid hormone increased (P < 0.001). The variation of urinary calcium correlated with that of cross-links (r = 0.73, P < 0.04). In long-HPN, OC was low or low-normal in almost all the patients, and cross-links were normal. Mean OC was lower than that of short-HPN both at baseline (P < 0. 003) and at follow-up (P < 0.002). The results suggest that in the early period of HPN bone metabolism improved from a hyperkinetic turnover to a positive balance. A low bone-formation rate appeared to be a characteristic feature of long-term HPN.
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