• Tiziana Ciarambino, Nicoletta Ferrara, Pietro Castellino, Giuseppe Paolisso, Ludovico Coppola, and Mauro Giordano.
• Department of Gerontology, Geriatrics and Metabolic Diseases, Second University of Naples, Naples, Italy.
• Nutrition. 2011 Jan 1; 27 (1): 46-49.

ObjectivesLate-life depression is one of the main health problems among elderly diabetic subjects. In addition, depression is a common psychopathological condition among renal failure patients and most of these patients follow a low protein diet regimen (LPD). However, the effects of LPD on depressive symptoms are unclear.DesignIn the present study, the effects of LPD regimen on depressive symptoms in elderly type 2 diabetic subjects with renal failure were investigated.ParticipantsFifty-two young-old type 2 diabetic patients with renal failure were enrolled in the study. All participants after normal protein diet regimen providing 1.2g/kg per d were instructed to consume either a LPD providing 0.8 g/kg per d, 7 d a wk (LPD 7/7), or a LPD providing 0.8 g/kg per d 6 d a wk (LPD 6/7) randomly.ResultsMean 15-item Geriatric Depression Scale (GDS-15) (2.0±0.6) and Beck Depression Inventory (BDI) (4.1±1.0), during normal protein diet regimen, significantly increased to (6.7±1.6) and (12.2±1.4), respectively, after LPD 7/7 (P<0.05 versus normal protein diet). However, after LPD 6/7, mean GDS-15 and BDI significantly decreased to (4.4±1.5) and (6.7±1.6), respectively (P<0.05 versus LPD 7/7).ConclusionLPD 6/7 regimen significantly decreased depressive symptoms in young-old type 2 diabetic patients.Copyright © 2011 Elsevier Inc. All rights reserved.

21 keywords...

hide…