• Resuscitation · Sep 2018

    Randomized Controlled Trial

    Umbilical cord milking in preterm neonates requiring resuscitation: A randomized controlled trial.

    • G Ram Mohan, A Shashidhar, B S Chandrakala, S Nesargi, and P N Suman Rao.
    • Department of Neonatology, St. John's Medical College Hospital, Bangalore, India.
    • Resuscitation. 2018 Sep 1; 130: 88-91.

    ObjectiveTo evaluate the effect of cord milking on short term morbidity and hematologic parameters at 6 weeks in preterm neonates requiring resuscitation.MethodsThis trial randomized preterm infants requiring resuscitation to milking group and no milking group. Multiple pregnancy, Rh negative mothers, hydrops, cord abnormalities were excluded. The primary outcome was hemoglobin and serum ferritin at 6 weeks of life. Secondary outcomes were common preterm morbidities and mortality.Results60 neonates were included in the study. Infants in the milking group had higher hemoglobin (10.07 g/dl vs 8.9 g/dl; p 0.003) and higher serum ferritin level (244.8 ng/ml vs 148.5 ng/ml; p 0.04) compared to no milking group.ConclusionsIn preterm neonates requiring resuscitation, umbilical cord milking results in higher hemoglobin and ferritin at 6 weeks of life. It can be a used as a placental transfusion strategy in preterm neonates requiring resuscitation with no significant adverse effects.Clinical Trial RegistrationClinical trials registry -India CTRI/2015/01/005436, www.ctri.nic.in.Copyright © 2018 Elsevier B.V. All rights reserved.

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