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Neuroimaging Clin. N. Am. · May 2018
ReviewImaging of Sjögren Syndrome and Immunoglobulin G4-Related Disease of the Salivary Glands.
- Akifumi Fujita.
- Department of Radiology, Jichi Medical University School of Medicine, 3311-1, Yakushiji, Shimotsuke, Tochigi 329-0498, Japan. Electronic address: akifuji@jichi.ac.jp.
- Neuroimaging Clin. N. Am. 2018 May 1; 28 (2): 183-197.
AbstractThe salivary glands are commonly affected in systemic autoimmune disease and diseases of unknown pathogenesis. Sjögren syndrome (SjS) can be affected by other systemic diseases. Immunoglobulin G4-related disease (IgG4-RD) commonly affects salivary glands. Imaging findings are usually nonspecific; however, radiologists should be familiar with the manifestations to avoid diagnostic delay. Findings of early-stage SjS are difficult to identify on routine computed tomography or MR imaging. Chronic SjS can be diagnosed from MR imaging and sialographic findings. Multiglandular and localized involvement of IgG4-RD is difficult to differentiate from malignant lymphoma for multiglandular disease and salivary gland carcinoma for localized disease.Copyright © 2018 Elsevier Inc. All rights reserved.
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