• Graham Nichol, Michael R Sayre, Federico Guerra, and Jeanne Poole.
• University of Washington-Harborview Center for Prehospital Emergency Care, University of Washington, Seattle, Washington. Electronic address: nichol@uw.edu.
• J. Am. Coll. Cardiol. 2017 Sep 19; 70 (12): 1496-1509.

AbstractCardiac arrest is defined as the termination of cardiac activity associated with loss of consciousness, of spontaneous breathing, and of circulation. Sudden cardiac arrest and sudden cardiac death (SCD) are terms often used interchangeably. Most patients with out-of-hospital cardiac arrest have shown coronary artery disease or symptoms during the hour before the event. Cardiac arrest is potentially reversible by cardiopulmonary resuscitation, defibrillation, cardioversion, cardiac pacing, or treatments targeted at the underlying disease (e.g., acute coronary occlusion). We restrict SCD hereafter to cardiac arrest due to ventricular fibrillation, including rhythms shockable by an automatic external defibrillator (AED), implantable cardioverter-defibrillator (ICD), or wearable cardioverter-defibrillator (WCD). We summarize the state of the art related to defibrillation in treating SCD, including a brief history of the evolution of defibrillation, technical characteristics of modern AEDs, strategies to improve AED access and increase survival, ancillary treatments, and use of ICDs or WCDs.Copyright © 2017 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

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