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- Samer Masri, Li S Zhang, Hao Luo, Edward Pace, Jinsheng Zhang, and Shaowen Bao.
- Neuroscience Graduate Program, University of Arizona, Tucson, AZ 85724, United States.
- Neuroscience. 2018 May 21; 379: 428-434.
AbstractBlast exposure can cause various auditory disorders including tinnitus, hyperacusis, and other central auditory processing disorders. While this is suggestive of pathologies in the central auditory system, the impact of blast exposure on central auditory processing remains poorly understood. Here we examined the effects of blast shockwaves on acoustic response properties and the tonotopic frequency map in the auditory cortex. We found that multiunits recorded from the auditory cortex exhibited higher acoustic thresholds and broader frequency tuning in blast-exposed animals. Furthermore, the frequency map in the primary auditory cortex was distorted. These changes may contribute to central auditory processing disorders.Copyright © 2018 IBRO. Published by Elsevier Ltd. All rights reserved.
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