• Neuroscience · Dec 1976

    Arylsulphatase A and 2',3'-cyclic nucleotide 3'-phosphohydrolase activities in the brains of myelin deficient mutant mice.

    • L L Sarlieve, A A Farooqui, G Rebel, and P Mandel.
    • Centre de Neurochimie du CNRS, and Institut de Chimie Biologique, Faculté de Médecine, 11 rue Humann, 67085 Strasbourg, France.
    • Neuroscience. 1976 Dec 1; 1 (6): 519-22.

    AbstractArylsulphatase A and 2',3'-cyclic nucleotide 3'-phosphohydrolase activities of myelin deficient mutant mice brains were studied. The results indicated that there were no changes in arylsulphatase A activity of the developing mutant brain, whereas the activity of 2',3'-cyclic nucleotide 3'-phosphohydrolase decreased considerably. The data obtained in this study suggest that in brain arylsulphatase A activity is localized in cells other than oligodendroglia.

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