• M Beaussier, A Decorps, P Tilleul, P Balladur, and A Lienhart.
• Department of Anesthesia and Intensive Care, Pharmacy, and Digestive Surgical Unit, St-Antoine University Hospital, Paris, France. mark.beaussier@sat.ap-hop-paris.fr
• J Clin Anesth. 2000 Dec 1; 12 (8): 586-91.

Study ObjectiveTo evaluate the rate of awakening after desflurane (D) or isoflurane (I) anesthesia when used during daily clinical practice.DesignObservational prospective study.SettingUniversity-affiliated metropolitan hospital.Patients68 ASA physical status I and II patients (18-75 yrs) scheduled for abdominal surgeries.InterventionsPatients scheduled for abdominal surgery of various duration received either D or I. No time was specified for discontinuation of the inhaled drugs at the end of the surgery. T0 for recovery parameters was stated as the end of the surgery. A p-value < 0.05 was considered as significant. Results are expressed as medians and ranges.Measurements And Main Results68 patients (32 in D group and 36 in I group) were analyzed. Patient demographic data were similar between the two groups. Duration of surgery was 151 minutes (83-428 min) and 174 minutes (40-552 min) for I and D, respectively. Extubation occurred earlier after D (18 min [9-35 min]) as compared to I (32 min [7-77 min]). Time to reach the Aldrete score at 10 was faster after D (30 min [12-45]) as compared to I (46 min [15-110]). Unlike I, the rate of awakening after D was independent of the duration of surgery. The differences between D and I reached statistical significance in surgical procedures lasting more than 100 minutes.ConclusionUsed during routine conditions, D allows for faster recovery than I in surgical procedures lasting more than 100 minutes. The rate of awakening after D remained independent of the duration of the surgical procedure.

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