• Med. J. Aust. · Mar 2014

    Treatment and prevention of Mycobacterium ulcerans infection (Buruli ulcer) in Australia: guideline update.

    • Daniel P O'Brien, Grant Jenkin, John Buntine, Christina M Steffen, Anthony McDonald, Simon Horne, N Deborah Friedman, Eugene Athan, Andrew Hughes, Peter P Callan, and Paul D R Johnson.
    • Barwon Health, Geelong, VIC, Australia. danielo@barwonhealth.org.au.
    • Med. J. Aust. 2014 Mar 17; 200 (5): 267-70.

    Abstract• Guidelines reflecting contemporary clinical practice in the management of Buruli ulcer (Mycobacterium ulcerans infection) in Australia were published in 2007. • Management has continued to evolve, as new evidence has become available from randomised trials, case series and increasing clinical experience with oral antibiotic therapy. • Therefore, guidelines on the diagnosis, treatment and prevention of Buruli ulcer in Australia have been updated. They include guidance on the new role of antibiotics as first-line therapy; the shortened duration of antibiotic treatment and the use of all-oral antibiotic regimens; the continued importance, timing and role of surgery; the recognition and management of paradoxical reactions during antibiotic treatment; and updates on the prevention of disease.

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