• Annals of surgery · Jan 2021

    Observational Study

    The Cost of Postoperative Complications and Economic Validation of the Comprehensive Complication Index: Prospective Study.

    • Roberto de la Plaza Llamas, Álvaro Hidalgo Vega, Raquel A Latorre Fragua, Aylhín J López Marcano, Aníbal A Medina Velasco, Daniel A Díaz Candelas, José M García Gil, and José M Ramia Ángel.
    • Department of General and Digestive Surgery, Hospital Universitario de Guadalajara, Spain.
    • Ann. Surg. 2021 Jan 1; 273 (1): 112-120.

    ObjectiveTo validate the Comprehensive Complication Index (CCI) via an assessment of its relation to postoperative costs.BackgroundThe CCI summarizes all the postoperative complications graded by the Clavien-Dindo classification (CDC) on a numerical scale. Its relation to hospital costs has not been validated to date.MethodsProspective observational cohort study, including all patients undergoing surgery at a general surgery service during the 1-year study period. All complications graded with the CDC and CCI and related to the initial admission, or until discharge if the patient was readmitted within 90 days of surgery, were included. The surgeries were classified according to their Operative Severity Score (OSS) and in 4 groups of homogeneous surgeries. All postoperative costs were recorded.ResultsIn all, 1850 patients were included, of whom 513 presented complications (27.7%). The CDC and the CCI were moderately to strongly correlated with overall postoperative costs (OPCs) in all OSS groups (rs = 0.444-0.810 vs 0.445-0.820; P < 0.001), homogeneous surgeries (rs = 0.364-0.802 vs 0.364-0.813; P < 0.001), prolongation of postoperative stay (rs = 0.802 vs 0.830; P < 0.001), and initial operating room costs (rs = 0.448 vs 0.451; P < 0.001). This correlation was higher in emergency surgery. With higher CDC grades, the OPC tended to increase an upward trend. In the multivariate analysis, CDC, CCI, age, and duration of surgery were all associated with OPC (P < 0.001).ConclusionsIn our environment, the CCI presented associations with OPC. This demonstration of its economic validity enhances its clinical validity.Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.

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