• J Anal Toxicol · Sep 1997

    Excretion of cannabinoids in urine after ingestion of cannabis seed oil.

    • T Lehmann, F Sager, and R Brenneisen.
    • Institute of Pharmacy, University of Bern, Switzerland.
    • J Anal Toxicol. 1997 Sep 1; 21 (5): 373-5.

    AbstractGas chromatographic-mass spectrometric (GC-MS) quantitation of 25 cannabis sed oils determined delta 9-tetrahydrocannabinol (THC) concentrations from 3 to 1500 micrograms/g oil. In a pilot study, the morning urine of six volunteers who had ingested 11 or 22 g of the oil, which contained the highest THC content (1500 micrograms/g), was collected for six days. The urine samples were screened by immunoassay, and the content of 11-nor-9-carboxy-delta 9-THC (THCCOOH) was determined by GC-MS. Urine samples were found cannabis positive for up to six days with THCCOOH-equivalent concentrations up to 243 ng/mL. by the Abuscreen OnLine immunoassay and THCCOOH contents from 5 to 431 ng/mL by the GC-MS method. All subjects reported THC-specific psychotropic effects.

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