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- A Schienle, S Übel, and W Scharmüller.
- Department of Clinical Psychology, University of Graz, Universitätsplatz 2/III, A-8010 Graz, Austria. Electronic address: anne.schienle@uni-graz.at.
- Neuroscience. 2014 Mar 28;263:125-9.
AbstractPlacebo treatment can alter brain activation in regions implicated in affective processing and cognitive control of emotions. This functional magnetic resonance imaging (fMRI) study investigated whether a placebo can additionally modulate visual cortex activity and connectivity during affective picture perception. The participants underwent a retest design where they were presented with disgusting, fear-eliciting and neutral pictures both with, and without a placebo (inert pill presented with the suggestion that it can reduce disgust symptoms). The placebo provoked a strong decrease in experienced disgust. This was accompanied by a reduced activation of the primary visual cortex, which showed reduced interaction with the amygdala and the insula. Accordingly, placebos are able to affect basic perceptive processes.Copyright © 2014 IBRO. Published by Elsevier Ltd. All rights reserved.
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