• Michael T Vest, Emma Newell, Mary Shapero, Patricia McGraw, Claudine Jurkovitz, Shannon L Lennon, and Jillian Trabulsi.
• Critical Care Medicine, Department of Medicine, Christiana Care Healthcare System, Christiana Care Value Institute, Newark, Delaware, USA, Sidney Kimmel Medical College, Philadelphia, Pennsylvania, USA. Electronic address: Mvest@christianacare.org.
• Nutrition. 2019 Oct 1; 66: 48-53.

ObjectivesThe aims of this study were, first, to compare the predicted (calculated) energy requirements based on standard equations with target energy requirement based on indirect calorimetry (IC) in critically ill, obese mechanically ventilated patients; and second, to compare actual energy intake to target energy requirements.MethodsWe conducted a prospective cohort study of mechanically ventilated critically ill patients with body mass index ≥30.0 kg/m2 for whom enteral feeding was planned. Clinical and demographic data were prospectively collected. Resting energy expenditure was measured by open-circuit IC. American Society of Parenteral and Enteral Nutrition (APSPEN)/Society of Critical Care Medicine (SCCM) 2016 equations were used to determine predicted (calculated) energy requirements. Target energy requirements were set at 65% to 70% of measured resting energy expenditure as recommended by ASPEN/SCCM. Nitrogen balance was determined via simultaneous measurement of 24-h urinary nitrogen concentration and protein intake.ResultsTwenty-five patients (mean age: 64.5 ± 11.8 y, mean body mass index: 35.2 ± 3.6 kg/m2) underwent IC. The mean predicted energy requirement was 1227 kcal/d compared with mean measured target energy requirement of 1691 kcal/d. Predicted (calculated) energy requirements derived from ASPEN/SCCM equations were less than the target energy requirements in most cases. Actual energy intake from enteral nutrition met 57% of target energy requirements. Protein intake met 25% of target protein requirement and the mean nitrogen balance was -2.3 ± 5.1 g/d.ConclusionsPredictive equations underestimated target energy needs in this population. Further, we found that feeding to goal was often delayed resulting in failure to meet both protein and energy intake goals.Copyright © 2019 The Authors. Published by Elsevier Inc. All rights reserved.

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