• Shunsuke Murata, Rei Ono, Junichi Omata, Tatsuya Endo, and Koji Otani.
• Department of Community Health Sciences, Kobe University, Graduate School of Health Sciences, Kobe, Hyogo, Japan; Japan Society for the Promotion of Science, Chiyoda, Tokyo, Japan.
• J Am Med Dir Assoc. 2019 Oct 1; 20 (10): 1263-1267.e3.

ObjectivesCoexistence of chronic musculoskeletal pain and depressive symptoms is common, and their combined effect on adverse events warrants investigation. The purpose of this study was to investigate the individual and combined effect of chronic musculoskeletal pain and depressive symptoms on the onset of disability, which is a crucial outcome in older adults.DesignA 1-year cohort study.Setting And Participants1251 community-dwelling older adults.MeasurementsThe number of chronic musculoskeletal pain sites was measured using a self-reported questionnaire. Depressive symptoms were assessed using the Geriatric Depression Scale-15. Disability was self-reported as any difficulty in basic activities of daily living. Incidence of disability was defined as any difficulty in performing 1 or more tasks at the follow-up assessment, that was absent at baseline.ResultsOlder adults with more chronic musculoskeletal pain sites tend to have depressive symptoms at baseline (P for trend < .001). Compared to older adults without both chronic musculoskeletal pain and depressive symptoms, older adults with both chronic multisite musculoskeletal pain and depressive symptoms have the higher risk for development of disability (adjusted odds ratio: 6.84, 95% confidence interval: 3.72 to 12.58), followed by older adults with chronic multisite musculoskeletal pain and without depressive symptoms (adjusted odds ratio: 2.13, 95% confidence interval: 1.35 to 3.37).Conclusions/ImplicationsSimultaneous assessment of both chronic musculoskeletal pain and depressive symptoms may be useful for accurate prognosis and preventing disability in older adults.Copyright © 2019 AMDA – The Society for Post-Acute and Long-Term Care Medicine. Published by Elsevier Inc. All rights reserved.

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