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Minerva endocrinologica · Dec 2001
[Efficacy of somatostatin analogs in the treatment of neuroendocrine tumours and paraneoplastic syndromes].
- P Sperlongano, M De Falco, D Pisaniello, D Parmeggiani, and U Parmeggiani.
- Istituto di Chirurgia Sperimentale, V Divisione di Chirurgia Generale e Tecniche Speciali Chirurgiche, Seconda Università degli Studi, Naples, Italy.
- Minerva Endocrinol. 2001 Dec 1; 26 (4): 293-5.
BackgroundThe authors report their experience with octreotide LAR in the adjuvant treatment of 10 patients suffering from neuroendocrine tumours and paraneoplastic syndromes.MethodsAll patients were studied preoperatively using traditional radiology and scintigraphy using octreoscan.ResultsOctreoscan was positive in all cases for somatostatin receptors. All patients with neuroendocrine tumours underwent surgery of the primary neoplasm; treatment with somatostatin was commenced at a later stage.ConclusionsThe authors' experience with octreotide LAR proved to be an efficacious means of controlling symptoms and stabilising disease without collateral effects. They conclude by affirming that octreotide LAR represents a valid therapeutic choice in the symptomatic treatment of neuroendocrine tumours.
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