• Hyun Ho Choi, Su Hwan Lee, Eung Koo Yeon, Dong Hyun Yoo, Young Dae Cho, Won-Sang Cho, Jeong Eun Kim, Young-Je Son, Moon Hee Han, and Hyun-Seung Kang.
• Department of Neurosurgery, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea.
• World Neurosurg. 2019 Dec 1; 132: e766-e774.

BackgroundRecurrence is one of the concerns even after successful endovascular treatment of intracranial aneurysms. We sought to determine the critical aneurysm volume and risk factors related to aneurysmal stability in patients undergoing coil embolization of intracranial aneurysms.MethodsAneurysm volume and follow-up imaging data were retrieved in 3042 patients with 3530 aneurysms who were treated with endovascular coil embolization from January 2006 to October 2016. We analyzed the anatomic outcome in relation to aneurysm volume and determined the critical aneurysm volume favoring coil embolization.ResultsRecanalization rates were 2.8%, 6.3%, 19.4%, and 67.4% in each group with aneurysm volume of <10, 10-100, 100-1000, and >1000 mm3, respectively. When we investigated the 100-1000 mm3 group, the recanalization rate remarkably increased at 500 mm3 (16.4% vs. 57.5%, P < 0.0001; odds ratio [OR], 6.968; 95% confidence interval [CI], 3.562-13.631). In the entire cohort, recanalization rates were significantly different between aneurysm volume of <500 and >500 mm3 (7.2% vs. 62.9%, respectively; P < 0.0001; OR, 21.848; 95% CI, 13.944-34.235). In aneurysm volumes of >500 mm3, the location was a significant prognostic factor for long-term stability (posterior circulation vs. anterior circulation; OR, 4.737; 95% CI, 1.275-17.602; P = 0.020).ConclusionsIn our series of cerebral aneurysms treated with coil embolization, 500 mm3 was found to be the critical volume determining stability after coil embolization. Large volume aneurysms in the posterior circulation were especially prone to recanalization after coiling.Copyright © 2019 Elsevier Inc. All rights reserved.

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