• Yoshinaga Okugawa, Yumiko Shirai, Hiroko Nodono, Fukumi Matsutani, Mari Itoh, Asahi Hishida, Yuki Morimoto, Ryutaro Nishikawa, Takeshi Yokoe, Koji Tanaka, Hisashi Urata, Yuji Toiyama, Toshimitsu Araki, Yasuhiro Inoue, Motoyoshi Tanaka, Masato Kusunoki, and Chikao Miki.
• Department of Surgery, Iga City General Hospital, Mie, Japan yoshinaga.okugawa@gmail.com harborne3030@gmail.com.
• Anticancer Res. 2017 Jan 1; 37 (1): 267-275.

BackgroundIn palliative care, prediction of life expectancy is one of the most crucial issues for patients, family and medical staff, in order to provide appropriate end-of-life care. The aim of this study was to formulate a new objective score to predict life expectancy within 1 week for terminally ill patients with cancer.Patients And MethodsMedical records were obtained from 187 terminally-ill patients with cancer who were admitted for palliative care. The biomarkers for a potential 'Objective Predictive Score' were assessed.ResultsProfiling of blood parameters demonstrated that elevated levels of alanine aminotransferase (ALT), total bilirubin (T-bil), blood urea nitrogen (BUN), creatinine (Cr) and a decreased platelet count were significantly correlated with death within 1 week in a training cohort. Our formulated Objective Predictive Score was able to predict death within 1 week with high accuracy in a training and a validation cohort.ConclusionOur scoring system might enable the assessment of prognostication with higher accuracy in a terminal care setting.Copyright© 2017 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.

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